Picocides For Bacteria, Insects, Fungi, and Virus Control

Pico Technology LLC
805 Cottage Hill Way, Brandon, FL 33511 800 995-9203, 336 306-0193
Email: Email donwilshe@biobased.us Emails go to spam, Best Call Us For Questions, Open 7 days EST 10AM to 10PM!

Picotechnology are Atoms made of (Protons, Neutrons & Electrons), And is Game Changer for all industries, For Agriculture "PicoAG 4-N-1 product" made of only atoms 1000 times smaller than nano and made of femto elements! Pico Ag a single product will replace Ag chemicals, Ag Fertilizer, Ag Remediation, Ag Pesticides, No Side Effects with a single product of atoms 100% organic matter. So this begs the questions why isn't Picotechnology taught in any worldwide university, because their would be no Agri-Chem, Phrama or Cleaning as we know it! Picotechnology will eliminate says university millions of employed! The purge has started and 5000 new products will hit the marketplace! Change the way people think and basis technology and people will never be the same!

World Speaking Invitations, To present our work on Picotechnology 1000 times smaller than Nano! PicoTechnology vs Nanotechnology
1) Dubai Speaker: 3rd World Congress & Expo on Nanotechnology and Materials Science during March 25-26, 2019 Dubai, UAE PicoTechnology vs Nanotechnology
2) Spain Speaker: World Chemistry Forum Nano Science Technology, May 22-24, 2019 in Barcelona, Spain. PicoTechnology vs Nanotechnology

In 2016 we had 2 agriclture journals papers published,and working on 2 more now!
Ramesh Ravella Sweet Sorghum 1312015AJEA23608 Biofuel Feedstock Cut fertilizer by 50% increase crop production!
Ramesh Ravella Canola Bio-Material Analyses of Two Canola Cultivars Cut fertilizer by 50% increase crop production!

The Picocides Science,                 For Pico Medicines,                 Home of Picotechnology

How does "PicoAg 4N1 25B" affect Pests?
As a pesticide you need a multipurpose mode of action for each pests you want to control.
Bacteria has a cell membrane and you have to puncture it and drain proteins and lipid.
Fungi which is made of cellulose and chitin need elimination.
Viruses need elimination strands of nucleic acid, either DNA or RNA, and protective protein coat (the capsid), Or a lipid envelope, surrounding the protein.

"PicoAg 4n1" immediately impacts the exoskeleton structure of the pest upon contact by disrupting the molecular structure of the chitin and other protein substances that protect the insect. This mechanism of action triggers the rapid and irreversible deterioration of the insect's spiracles and tracheal system, resulting in suffocation. "PicoAg 4N1 25B" kills insects with elimination of chitin is a polysaccharide, a carbohydrate that has a chain sugar molecules, Chitin is a structure like cellulose. In addition to being found in exoskeletons.

"PicoAg 4N1 25B" major benefit of this revolutionary method of insect control is the absence of undesirable side effects on human health and no harm to the ecosystem. Additionally, unlike standard insecticides in use today, no built-in resistance can be developed by the targeted insects, since this new insecticide does not act on the nervous system, but rather on the respiratory apparatus."

Science suggests that "PicoAg 4N1 25B" can be mechanical in primary sequential steps:
The first step is a direct interaction between the surface and the pests outer membrane, causing the membrane to rupture and leak water, proteins and nutrients.
A second step related to the holes in the outer membrane, through which the pests lose vital nutrients, protein, lipids, water and components, causing general weakening of pests.
Lastly a few more ways electromechanical can affect pests
Electromechanical in "PicoAg 4N1 25B" can affect pests by penetration and dissolve lipid cellular membranes.
This causes cells desiccation to leak water, proteins and nutrients and collapse.
By interfering with cellular metabolism during metamorphosis.
By dissolving cuticles the lubrication in the insect’s joints leading to paralysis.
By stripping the pests protective shields (wax, biofilm, etc), rendering it defenseless against subsequent treatment.
The extracts impact the exoskeleton structure of pests upon contact by disrupting the molecular structure of the chitin and other protein substances that protect the insect.
The extracts have the ability to penetrate complex hydrocarbon chains and disintegrate them.
The extracts emulsify pests thus stopping their reproduction cycle.
The change the environment for growth with PH from acidophiles and neutrophiles to alkaliphiles.

After punching holes, how does "PicoAg 4N1 25B" further damage the cell?

Now that the cells main defense (its outer envelope) has been breached, there is an unopposed stream of "PicoAg 4N1 25B" entering the cell. This puts several vital processes inside the cell in danger. "PicoAg 4N1 25B" literally overwhelms the inside of the cell and obstructs cell metabolism (i.e., the biochemical reactions needed for life). These reactions are accomplished and catalyzed by enzymes. When "PicoAg 4N1 25B" binds to these enzymes, their activity grinds to a halt. Pests can no longer "breathe", "eat", "digest", “reproduce” or “exist”.

How can "PicoAg 4N1 25B" punch holes in a pests?

Every cell's outer membrane, including that of a single cell organism like a pests, is characterized by a stable electrical micro-current. This is often called "transmembrane potential", and is literally, a voltage difference between the inside and the outside of a cell. It is strongly suspected that when a pests comes in contact with a "PicoAg 4N1 25B" surface, a short circuiting of the current in the cell membrane can occur. This weakens the membrane and creates holes and leak water, proteins and nutrients.

How can "PicoAg 4N1 25B" effect be so fast, and affect such a wide range of pests?

Experts explain the speed with which pests and other pests perish on "PicoAg 4n1" surfaces by the multi-targeted "PicoAg 4N1 25B" effects. After membrane perforation, can inhibit any given enzyme that "stands in its way," and stop the cell from transporting or digesting nutrients, from repairing its damaged membrane, from breathing or multiplying. Harmless to Environment Air, Water, Soil, Humans, Birds and Animals. This new science has no side effects or harm on human, birds and animal health. These solutions do not harm mammal cells nor do they attack neurological systems of humans, birds and animals.

Science suggests that "PicoAg 4N1 25B" can be mechanical in primary sequential steps:

Bacteria's Fungi's Virus's Insects's Nursery Tours's
Picotechnology-Industries Pico-Medicine Picocides Pico-Technology Picosoap

Total Atoms Per Acre Atoms Per Foot Atoms Per Sq Inch
Total Atoms 416,931,197,021,738,000,000,000 12,063,981,395,304,900,000 83,777,648,578,506,400
The Carbon(C) 376,071,939,713,608,000,000,000 10,881,711,218,565,000,000 75,567,439,017,812,800

Nitrogen (N) 33,354,495,761,739,100,000,000 965,118,511,624,394,000 6,702,211,886,280,520
Phosphorus (P) 667,089,915,234,781,000,000 19,302,370,232,487,900 134,044,237,725,610
Potassium (K) 958,941,753,149,998,000,000 27,747,157,209,201,300 192,688,591,730,565
Calcium (Ca) 875,555,513,745,650,000,000 25,334,360,930,140,300 175,933,062,014,864
Magnesium (Mg) 667,089,915,234,781,000,000 19,302,370,232,487,900 134,044,237,725,610
Sulfur (Su) 625,396,795,532,607,000,000 18,095,972,092,957,400 125,666,472,867,760
Zinc (Zn) 25,015,871,821,304,300,000 723,838,883,718,296 5,026,658,914,710
Manganese (Mn) 50,031,743,642,608,600,000 1,447,677,767,436,590 10,053,317,829,421
Iron (Fe) 75,047,615,463,912,900,000 2,171,516,651,154,890 15,079,976,744,131
Copper (Cu) 4,169,311,970,217,380,000 120,639,813,953,049 837,776,485,785
Boron (B) 16,677,247,880,869,500,000 482,559,255,812,197 3,351,105,943,140
Sodium (Na) 250,158,718,213,043,000,000 7,238,388,837,182,960 50,266,589,147,104
Chlorine (Cl) 500,317,436,426,086,000,000 14,476,777,674,365,900 100,533,178,294,208
Molybdenum (Mo) 416,931,197,021,738,000,000 12,063,981,395,304,900 83,777,648,578,507
Aluminum (Al) 488,893,521,627,690,000,000 14,146,224,584,134,600 98,237,670,723,157
Silicon (SI) 300,857,551,770,886,000,000 8,705,368,974,852,040 60,453,951,214,250

Editorial Reviews
About The Editor

This 700 page volume is developed on the broad theme of plant-associated bacteria. It is envisioned as a resource volume for researchers working with beneficial and harmful groups of bacteria associated with crop plants. The book is divided into two parts. Part I (9 chapters) on beneficial bacteria includes chapters on symbiotic nitrogen fixers, diazotrophs, epiphytes, endophytes and rhizosphere bacteria and deleterious rhizobacteria. Part II (8 chapters) consists of detailed descriptions of 8 genera of plant pathogenic bacteria: Agrobacterium, Clavibacter, soft-rot Erwinia, Pseudomonas, Xanthomonas, Ralstonia, Burkholderia and Acidovorax & Herbaspirillum. There is an opening chapter on the plant-associated bacteria survey, molecular phylogeny, genomics and recent advances. And each chapter includes terminology/definitions, molecular phylogeny, methods that can be used (both traditional and latest molecular tools) and applications.

About the Author

The Editor, Sam Gnanamanickam, is a plant pathologist and a rice biotechnologist. He obtained his Ph.D degree in plant pathology from the University of Hawaii in 1976. On his return to India he took up a lecturer's position in plant pathology at the Centre for Advanced Studies in Botany of the University of Madras, India in 1978 and has moved up as Reader and Professor in the same Department. He has had postdoctoral training at Agriculture Canada (1980-82) and was a Visiting Scientist at the International Rice Research Institute (IRRI), Los Banos, Philippines during 1987-89. He was associated with the International Rice Biotechnology net-work program supported by the Rockefeller Foundation for 10 years (1990-2000) which helped him to develop collaborative research with several advanced laboratories on molecular breeding of rice and biological control of rice diseases. He was accepted as an Adjunct Professor of Plant Pathology at the University of Arizona in 2004 and was elected as a Fellow of the National Academy of Agricultural Sciences, New Delhi in 2005. His earlier book on Biological Control of Crop Diseases was published by Marcel Dekker, NY, 2002.
Applications for Pico-Technology Websites:

Pico Technology LCC
Donald Wilshe
805 Cottage Hill Way
Brandon, Fl 33511
Email: donwilshe@biobased.us
Phone USA 800 995-9203 Direct to Cell.
Phone USA INTL 336-306-0193


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